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Nickel Sensitivity DNA Test
Nickel is found in everyday items, but some people are genetically sensitive to it. This DNA test identifies your risk of allergic reactions—like skin irritation, fatigue, or digestive issues—and provides personalised insights on exposure management, diet adjustments, and prevention strategies to help you better protect your health and overall wellbeing
Easy and simple sample collection
results will be available within 10 to 15 working days
$89
- Identify genetic nickel allergy risk
- Understand symptoms like dermatitis, fatigue
- Get personalised lifestyle recommendations
How it Works
How it Works
Key Features of the Nickel Sensitivity DNA Test
- Accurate
- Easy-To-Use Test Kit
- Fast
- Accredited
Our SkinCare DNA test is an extremely accurate test that will help you to discover your food and pet sensitivities. All of our tests meet international testing standards and guarantee maximum accuracy.
Our DNA testing kit will contain all you require to perform the test. We will send you oral swabs to rub on the inside of your mouth in order to collect cheek cells; hence, you will not need to go through painful blood sampling. All our kits contain comprehensive instructions. You can see online how easy it is to collect your DNA Samples.
Results will be issued within 30-45 working days from receipt of your samples at the laboratory. These are sent to you by email unless otherwise requested (additional charges may apply).
All home tests are performed by an ISO 17025 accredited laboratory which has performed over 250,000 DNA tests to date. You can, therefore, rest assured that your test is being performed under the strictest of guidelines.
Nickel Sensitivity and Allergy DNA Test
Nickel is a widely used metal found in everything from jewellery and coins to smartphones and even food. While harmless to most, some individuals experience allergic reactions when exposed to it. These reactions can range from skin irritation to more systemic symptoms such as digestive discomfort and chronic fatigue.
The Nickel Sensitivity DNA Test analyses genetic variants linked to how your body reacts to nickel. By identifying your genetic predisposition, this test helps you understand whether you're more likely to experience allergic responses and gives you the information you need to take control of your wellbeing.
What You’ll Learn from The Nickel Sensitivity DNA Test
This test explores two key genes involved in nickel sensitivity—FLG (Filaggrin) and TNF-α (Tumour Necrosis Factor Alpha). These genes are crucial in maintaining your skin barrier and regulating your immune system’s inflammatory responses. Understanding your results can empower you to make practical changes that reduce your risk of nickel-triggered reactions.
• Your Genetic Predisposition: Discover whether you carry genetic variants that may increase your sensitivity to nickel.
• Risk of Symptoms: Learn if you are more susceptible to conditions like Allergic Contact Dermatitis or Systemic Nickel Allergy Syndrome (SNAS)—a condition that can trigger digestive issues, fatigue, and more.
• Personalised Health Advice: Gain practical, DNA-based guidance on how to avoid nickel exposure, adjust
Want to see what your results will look like?
The Science Behind the Nickel Sensitivity Test
Nickel sensitivity is influenced by the way your body interacts with allergens. This DNA test focuses on two genetic markers that have been scientifically linked to allergic reactions and inflammatory responses.
FLG Gene (Filaggrin):
The FLG gene plays a critical role in creating and maintaining your skin’s protective barrier. Mutations in this gene can:
• Allow allergens like nickel to pass through the skin more easily
• Increase the likelihood of developing allergic contact dermatitis (itching, redness, blistering)
• Lead to chronic skin dryness, delayed healing, and increased skin sensitivity
TNF-α Gene (Tumour Necrosis Factor Alpha)
This gene encodes a pro-inflammatory cytokine that regulates immune responses. Unfavourable variants in this gene may:
• Heighten inflammatory reactions to nickel exposure
• Increase the risk of systemic symptoms including digestive upset, headaches, and fatigue
• Worsen pre-existing inflammatory skin conditions such as eczema
By identifying if you carry unfavourable variants in these genes, the test helps explain why you may react to nickel and how to manage your sensitivity proactively.
Gene spotlight: SLC30A3 and your brain's zinc balance
The SLC30A3 gene encodes a protein known as ZnT3, which is responsible for transporting zinc into synaptic vesicles in the brain. These vesicles play a key role in neuron-to-neuron communication and memory processing.
People with a specific variant of the SLC30A3 gene may have reduced ZnT3 function, which can impair zinc transport to critical areas in the brain. This has been linked to:
• Increased oxidative stress
• Impaired memory and cognitive decline
• Greater vulnerability to neurodegenerative disorders
While more research is ongoing, having an unfavourable version of this gene could suggest a need to monitor zinc intake more closely, especially if you experience memory issues or neurological symptoms.
Nickel Sensitivity DNA Test: a Simple Process
Getting tested couldn’t be easier. There’s no need for a blood sample or clinic visit. We’ll send you a home sample collection kit that includes sterile buccal swabs and clear instructions.
All you need to do is rub the swab inside your cheek, return the sample using the prepaid envelope, and we’ll do the rest.
• Open kit and complete forms
• Swab cheeks for one minute
• Dry swabs and send kit
Report Features & Results Format of the Nickel Sensitivity DNA Test
Your results come in a comprehensive and easy-to-understand report that includes:
• Clear Explanations – Learn what your genetic results mean and how they affect your sensitivity to nickel
• Summary Table – Quickly see how your genes performed and which areas may need attention
• Colour-Coded Results – Understand your risk level at a glance:
• Scientific References – For those who want to explore the research behind the results, the report includes a full bibliography
Understanding Nickel Sensitivity
Nickel intolerance can manifest in different ways. Here are the most common symptoms associated with sensitivity:
• Allergic Contact Dermatitis – Occurs when the skin touches nickel-containing objects like jewellery, watches, coins, or mobile phones. Symptoms include itching, rashes, redness, and even blistering.
• Systemic Nickel Allergy Syndrome (SNAS) – A more severe reaction triggered by dietary nickel. Common symptoms include bloating, diarrhoea, nausea, headaches, fatigue, and general malaise.
• Aggravated Chronic Conditions – Nickel exposure can worsen pre-existing conditions such as eczema, asthma, or gut inflammation.
Genetic predisposition doesn’t guarantee that you’ll develop symptoms—but knowing your risk helps you take the right precautions early.
This test is an important first step in understanding how your body responds to one of the most common environmental allergens. Whether you’ve experienced symptoms in the past or simply want to be proactive, the Nickel Sensitivity DNA Test offers valuable insights you can act on.
Your genetic results can guide your daily decisions—from what to eat to what skincare products to use—helping you avoid flare-ups, manage inflammation, and live more comfortably.
Other Options Beyond the Zinc-Iron Gene Check Test
For a more complete picture of your health, consider bundling the Carbohydrate Metabolism DNA Test with other related tests. The Nicotine Dependence Test reveals genetic factors linked to addiction, the Salt Sensitivity Test identifies your risk of high blood pressure from salt intake, and the Zinc-Iron Gene DNA Test analyses genes involved in mineral absorption. You can also explore tests like Lactose Intolerance and Caffeine Sensitivity to better understand how your body processes specific nutrients and substances. Bundling these tests offers a broader, personalised view of your health and supports more informed lifestyle choices.
Special Offers
The price of the Intolerance test is $99.
A second or third Intolerance test for a relative or a friend can be purchased at $89 ($10 discount).
We also offer a number of interesting Health Test like the Gut Microbiome Test, Vegetarian Food Intolerance test, DNA Diet and Healthy Weight Test and much more!
Disclaimer:This test does not provide medical advice or replace a doctor’s consultation. Do not make any health or medical decisions based on your results without first consulting a qualified doctor or specialist. Always seek professional medical guidance before taking any action.
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