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Folate Metabolism Test
Free Delivery
Results in 10-15 working days
From $59
- Identify potential deficiencies in your folate metabolism
- Easy-to-use Kit
- Support at every step of the process
How it Works
Key Features of the Folate Metabolism Test
- Accurate
- Easy-To-Use Test Kit
- Fast
- Accredited
Our SkinCare DNA test is an extremely accurate test that will help you to discover your food and pet sensitivities. All of our tests meet international testing standards and guarantee maximum accuracy.
Our DNA testing kit will contain all you require to perform the test. We will send you oral swabs to rub on the inside of your mouth in order to collect cheek cells; hence, you will not need to go through painful blood sampling. All our kits contain comprehensive instructions. You can see online how easy it is to collect your DNA Samples.
Results will be issued within 30-45 working days from receipt of your samples at the laboratory. These are sent to you by email unless otherwise requested (additional charges may apply).
All home tests are performed by an ISO 17025 accredited laboratory which has performed over 250,000 DNA tests to date. You can, therefore, rest assured that your test is being performed under the strictest of guidelines.
What is Folate Metabolism?
Folate metabolism is a complex biochemical process that involves the conversion of folate, a B-vitamin, into its active form. This active form, known as 5-methyltetrahydrofolate (5-MTHF), plays a crucial role in various bodily functions.
The MTHFR gene provides instructions for creating an enzyme called methylenetetrahydrofolate reductase. This enzyme is essential for converting folate into its active form, 5-MTHF.
5-MTHF is vital for several bodily functions, including:
• DNA Synthesis and Repair: It helps in the formation and repair of DNA, the genetic material of cells.
• Neurotransmitter Production: It contributes to the production of neurotransmitters, chemicals that transmit signals between nerve cells.
• Red Blood Cell Formation: It aids in the production of red blood cells, which carry oxygen throughout the body.
When talking about Vitamin B and Folate Metabolism, the question may arise as to what is the difference between Folate and Folic Acid:
• Folate: The natural form of vitamin B9 found in foods like leafy green vegetables, legumes, and fortified grains.
• Folic Acid: The synthetic form of vitamin B9 used in supplements and fortified foods.
Why should you take the Folate Metabolism Test?
A reduced ability to metabolize folate can lead to various health issues, such as:
• Neural Tube Defects: During pregnancy, insufficient folate can increase the risk of neural tube defects in the developing fetus.
• Cardiovascular Disease: Elevated homocysteine levels, a byproduct of impaired folate metabolism, can contribute to heart disease and stroke.
• Other Health Conditions: Poor folate metabolism may also be linked to other health problems, including certain types of cancer and cognitive decline.
Understanding your body’s folate metabolism can help you make informed decisions about your diet and supplement choices to optimize your health.
How the test works?
Understanding the MTHFR Gene
The MTHFR gene provides instructions for creating an enzyme called methylenetetrahydrofolate reductase (MTHFR). This enzyme plays a crucial role in converting folate, a B-vitamin, into its active form, 5-methyltetrahydrofolate (5-MTHF).
The MTHFR C677T variant is a specific genetic mutation that can affect the efficiency of the MTHFR enzyme. Individuals with this variant may have difficulty converting folate into its active form, 5-MTHF.
When the MTHFR enzyme is less efficient, it can lead to:
• Elevated Homocysteine Levels: Homocysteine is an amino acid that, when elevated, can increase the risk of heart disease and stroke.
• Impaired Folate Metabolism: Reduced ability to utilize folate for various bodily functions.
The severity of the MTHFR C677T variant depends on the number of mutated copies of the gene inherited:
• Heterozygous: One mutated copy (inherited from one parent). This can lead to a mild reduction in enzyme activity.
• Homozygous: Two mutated copies (inherited from both parents). This can lead to a significant reduction in enzyme activity, increasing the risk of health problems.
The price of the Folate Metabolism Test is $59.
Test Option: Homocysteine Metabolism (MTHFR-2 Gene)
The Connection Between Folate and Homocysteine
Folate and homocysteine are two important substances in the body that are closely linked. When folate levels are adequate, the body can efficiently convert homocysteine into other substances, such as methionine. However, when folate levels are low, homocysteine can build up in the blood.
Elevated Homocysteine: A Risk Factor
High levels of homocysteine in the blood, a condition known as hyperhomocysteinemia, can increase the risk of various health problems, including:
• Cardiovascular disease
• Stroke
• Dementia
As mentioned before, the MTHFR C677T variant is one of the most well-studied genetic variations that can affect MTHFR enzyme activity.
Another important variant is the MTHFR A1298C variant, also known as MTHFR-2. This variant can also impact folate metabolism and homocysteine levels.
When both the MTHFR C677T and MTHFR A1298C variants are present, the combined effect can be more pronounced. This can lead to a significant reduction in MTHFR enzyme activity and further increase the risk of elevated homocysteine levels.
By understanding the role of the MTHFR gene and its variants, individuals can take steps to optimize their folate intake and reduce their risk of health problems associated with elevated homocysteine levels.
The price of the Homocysteine Metabolism Test is $114.
Sample collection
Only a buccal swab sample is needed for the Folate Metabolism Test, the sample collection kit you will receive will allow you to collect your sample comfortably at home in a simple and safe way. Follow the instructions provided in the kit. You will receive the results of your Folate Metabolism Test in 10-15 working days.
Special Offers
The price of the Intolerance test is $99.
A second or third Intolerance test for a relative or a friend can be purchased at $89 ($10 discount).
We also offer a number of interesting Health Test like the Gut Microbiome Test, Vegetarian Food Intolerance test, DNA Diet and Healthy Weight Test and much more!
FAQs
A food sensitivity is a reaction of your body to food digested. Unlike a food allergy, if you suffer from food sensitivity the adverse reaction is generally delayed.
If you want to improve your health and have a better lifestyle it is recommended to understand if your body reacts to certain foods or not.
Many people struggle all their life with food intolerance, a suffering that can be avoided with a simple change in the diet.
Food sensitivity is a reaction of your body when you digest some specific foods. If you suffer from gas, bloating, fatigue, acne, diarrhea, or stomachache you may have a food sensitivity. Those reactions are not immediate.
Food intolerance is when your body does not have a specific enzyme, as a result after digesting some foods your body can’t break it down. The most common intolerance is lactose intolerance. If you suspect you may have an intolerance it is advised to take our Food & Pet Intolerance Test.
Red wine and other fermented foods or drinks may contain histamine. It is not uncommon that some people may have difficulties to break down this organic compound.
Inconclusive refers to an indeterminate result – hence the laboratory could not detect the alleles or a gene was not found. This is nothing wrong, it simply means that when analysing your sample the results were outside what the software expects, therefore the laboratory cannot say or not if there is a sensitivity.
No, you don’t need to take the Food & Pet Intolerance Test each year. The test analyses your DNA to discover your sensitivities and DNA does not alter throughout the years; therefore you won’t need to retake this test again.
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