Dog Multidrug Resistance 1 (MDR1) Test
Many dog breeds are afflicted by the MDR1 gene mutation, which affects how they react to certain drugs and medications. With our new Dog Multidrug Resistance 1 (MDR1) Test, you can determine if your dog carries the gene mutation, allowing you to take better care of your pet’s health. The price of the Dog MDR1 Test starts from $69.
Free Delivery
Results in 7-10 working days
from $69
- Test for the MDR1 gene mutation
- Gain peace-of-mind
- Easy-to-use kit
- Support at every step of the process
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How it Works
How it Works
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Key Features of the
Dog Multidrug Resistance 1 (MDR1) Test
Why test your dog for the MDR1 gene defect
The multidrug resistance mutation 1 (MDR1) refers to the mutation that occurs at the ABCB1 gene or MDR1 gene, which makes the animal more sensitive to the effects of certain drugs.
The MDR1 gene defect impairs your dog’s ability to accept important medications that protect them against illnesses as well as parasites. If your dog does have this gene defect, they can react to medicine adversely and, depending on the severity of the defect, even fatally.
For dogs that possess the gene mutation, higher levels of drugs enter their brain which increases the effects of common drugs such as the following:
Ivermectin, milbemycin, selamectin (parasite treatment)Loperamide (anti-diarrhoea)Acepromazine (tranquiliser)Butorphanol (pain relief)Doramectin, doxurubicin, emodepside, erythromycin (heartworm treatment)A dog that possesses the MDR1 gene mutation will require very careful considerations when it comes to medications and dosages. Aside from this, determining if your dog possesses the mutation will also help you make an informed decision about breeding.
How common is the MDR1 gene mutation among dogs?
Although it can occur with any dog, the MDR1 mutation is most commonly observed among purebred herding dog breeds. Mixed breed dogs carry a 35% risk of carrying the gene defect, while purebred dogs carry a much higher 75% risk.
For the MDR1 Test, these are the breeds that can be tested:
AussiedoodleAustralian Cobber DogAustralian ShepherdBorder CollieCollieCzech WolfdogCzech VlcakEnglish ShepherdGerman Shepherd DogLonghaired WhippetMcNab ShepherdMiniature Australian ShepherdOld English SheepdogShetland SheepdogShiloh ShepherdSmooth CollieWallerWhite ShepherdWhite Swiss ShepherdDogs inherit one copy of the MDR1 gene from each parent. If your dog happens to have inherited a defective copy of the gene from a parent, it puts them at risk of suffering the potentially life-threatening effects of the defect.
If your dog happens to have two defective copies of the gene, they may suffer even more severe side effects such as tremors, blindness, anorexia, excess salivation, and death.
Does your pet have the defect or not? The best way to determine this is to take a Dog Multidrug Resistance 1 (MDR1) Test.
Cost of the MDR1 test
The Dog MDR1 test is being offered at only $69 for a sample of one dog. There is an option to order more tests for an additional cost.
How the MDR1 test is carried out
Take away the guesswork with the EasyDNA MDR1 Test. It is a fast and reliable way to determine whether your dog possesses the MDR1 gene defect or not. This way, you can work with your veterinarian to address your pet’s specific medical needs.
The process of our MDR1 test is very straightforward. Upon ordering your test, we will send you a sample collection kit that allows you to collect your dog’s cheek swab samples. Using our kit, there is no need to draw blood or go to the veterinarian for sample collection.
Once you are able to collect your dog’s DNA sample following the instructions provided in the kit, all you need to do is send it back to our laboratory for testing.
Your test results
After our laboratory receives your dog’s sample, you can expect to receive your test results via email in 7-10 working days from receipt of samples at the laboratory. You will receive one of three possible outcomes:
CLEAR result: Your dog has inherited 2 good genes that are free from defects or mutations.CARRIER result: Your dog has inherited 1 normal copy of the gene and 1 mutated copy. This means that the animal may have an increased risk of suffering the effects of MDR1 gene mutation.AFFECTED result: Your dog has inherited 2 copies of the mutated MDR1 and is at risk of suffering adverse or life-threatening reactions to medications.EasyDNA uses the latest in DNA testing technology, assuring you that the results of your MDR1 test are highly accurate and reliable. If you need more information regarding this test, please contact our Customer Service or email us directly.
Other Dog Disease Genetic Tests from EasyDNA
At EasyDNA we offer a range inherited disease screening tests such as the MDR1 including the following:
Degenerative Myelopathy Test (DM)Exercise Induced Collapse Testing (EIC)Hyperuricosuria DNA Test for Uric AcidPRCD-pra Testingvon Willebrand Disease DNA TestingWe also offer a comprehensive genetic screening test covering 175+ diseases and traits through our DogCheck Genetic Screening Test. This is one of the most comprehensive tests on the market ideal to manage the health of your dog and for breeders.
Other Dog DNA Tests from EasyDNA
We also offer a wide range of other types of dog DNA tests looking at different personal aspects of your dog such as the Premium Dog Testing Package, an all-in-one testing package that includes our Dog Allergy Test, Dog Breed Test, and Dog Genetic Age Test.
Find out more about your dog and start your journey to a healthier pet!
Special Offers and Discounts
The price of the Dog Allergy test is $104.
A second or third Dog Allergy test for your other dog or maybe for a relative or a friend can be purchased at $94 ($10 discount). You can also benefit from a $14 discount if you decide to order a Dog Breed Test (priced at $79) with your Dog Allergy test. In addition, we are offering our clients the opportunity to purchase a premium package priced at $195 including 3 Dog tests, the Dog Genetic Age test, Breed test and Allergy test. Make use of our discounted prices to understand even better your beloved pet!
FAQs
We provide a testing kit containing the sample collection device and instructions for collecting your dog’s sample and sending it back to our laboratory. From the proteins found in the sample obtained, the test measures your dog’s sensitivities to over 120 common allergens.
Upon ordering the test, you will receive a testing kit with a sample collection device and complete sample collection instructions. Hold the swab firmly from the handle and place the swab head inside your dog’s mouth. Get the swab head as wet as possible by placing it under your dog’s tongue, the side of the mouth, and inside the cheek for 1 1/2 minutes.
A sample collection guide with pictures can be found HERE.
- Mold spores
- Dust and house dust mites
- Medications
- Insecticidal shampoo
- Rubber and plastic
This test has access to a database containing over 120 of the most common canine allergens. However, we are always working on adding more allergens to the testing database.
Click here for the most up-to-date allergen listings.
The test can determine sensitivities at any age, but these sensitivities can change as a dog ages. We recommend that your dog be at least 6 months old to identify specific allergens that may affect them for a long period of time.
Click here for the most up-to-date allergen listings.
Your dog should not eat before getting its sample collected as food can affect the test results. We recommend either taking your dog’s sample first thing in the morning or waiting for the longest possible time between meals to collect the sample.
Aside from food, there are also medications, such as antihistamines and steroids, that can affect the dog’s test results. Therefore, your dog must not be on any antihistamines, anti-itching and anti-inflammatory medication or steroid-based medications for 1-2 weeks before collecting its sample.
Click here for the most up-to-date allergen listings.
- Itchy, red, moist or scabbed skin
- Increased scratching
- Itchy, runny eyes
- Itchy ears and ear infections
- Sneezing
- Diarrhoea
- Snoring
- Constant licking
Know more about the dog allergies and symptoms HERE.
Aside from food, there are also medications, such as antihistamines and steroids, that can affect the dog’s test results. Therefore, your dog must not be on any antihistamines, anti-itching and anti-inflammatory medication or steroid-based medications for 1-2 weeks before collecting its sample.
Click here for the most up-to-date allergen listings.
Some dogs may be sensitive to chicken eggs but not chicken meat, while some dogs may be sensitive to fish meal but not a particular type of fish. This is normal. Each allergen has unique components and characteristics, and a dog’s reaction to an allergen may not necessarily equate to sensitivity to its subsets.
Yes, different dog breeds may be more susceptible to specific allergies.
The following are some breeds that are sensitive to issues with food and/or airborne allergies: Maltese terrier, Pekingese, German Shepherd, Bull Terriers, Bichon Frise, English Cocker Spaniel, Brussels Griffon, American Hairless Terrier, Bohemian Terrier, Shih Tzu, Lhasa Apso, American Pit Bull Terrier, Wire-Haired Fox Terrier, Chinese Crested/Powderpuff, Poodle, Irish Setter, English Bulldog, Pugs.
Are you interested to find out the breeds making up your dog? Take our Dog Breed DNA Test today.
Reactions can be managed by avoiding the allergens which trigger them. For example, if your pet has a sensitivity to a particular food item then eliminating this from their diet will help eliminate the negative impact. It is also possible to manage them through the use of medication or medicated shampoos – however, many times such treatments only mask a problem without finding the root cause. Also since more than one allergen may be causing reactions in your dog this may require more than action to eliminate all discomfort and reactions. We strongly advocate involving your vet in all decisions regarding what actions to take.
The following are some breeds that are sensitive to issues with food and/or airborne allergies: Maltese terrier, Pekingese, German Shepherd, Bull Terriers, Bichon Frise, English Cocker Spaniel, Brussels Griffon, American Hairless Terrier, Bohemian Terrier, Shih Tzu, Lhasa Apso, American Pit Bull Terrier, Wire-Haired Fox Terrier, Chinese Crested/Powderpuff, Poodle, Irish Setter, English Bulldog, Pugs.
Are you interested to find out the breeds making up your dog? Take our Dog Breed DNA Test today.
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